2012 - 2017 Ershela Durresi, Ph.D. Medical Student, Harvard Medical School . However, research on the predictive potential and clinical importance of mitophagy-related genes (MRGs) in hepatocellular carcinoma (HCC) is currently lacking. Dejanovic B, Huntley MA, De Mazire A, Meilandt WJ, Wu T, Srinivasan K, Jiang Z, Gandham V, Friedman BA, Ngu H, Foreman O, Carano RAD, Chih B, Klumperman J, Bakalarski C, Hanson JE, Sheng M. Neuron. NE30-6031. Dr. Sheng Ding is currently William K. Bowes, Jr. Morgan Sheng, a neurobiologist and physician-scientist with deep experience in both basic research and drug discovery, has joined the Broad Institute of MIT and Harvard as its newest Core Member and as Co-Director of the institute's Stanley Center for Psychiatric Research.He will also return to MIT, after a decade in industry, as a professor of neuroscience in the Department of Brain and . We've screened more than 1,275 cancer cell lines as part of the Cancer Dependency Map (DepMap). Sheng received a B.A. 213: 2009: ARF6 and EFA6A regulate the development and maintenance of dendritic . is author of more than 200 peer-reviewed publications focused on the molecular cellular biology of synapses and synaptic plasticity, and pathogenic mechanisms of neurodegenerative diseases. - Investigating stem cells, regeneration and ageing using Planarian flatworms. His work has uncovered the form and complexity of protein complexes in the postsynaptic membrane that regulate the remarkable plasticity of neuronal connections. Dr. Sheng lab haspublisheda number of important studies focused on axonal transport of mitochondria and endolysosomes in healthy and diseased neurons. Discover remarkable stories of scientific progress, and explore the intersections of science, medicine, and society. Just another site. Eye and Ear Institute 915 Olentangy River Road Suite 4000 Columbus, OH 43212. . From 2008 to 2019, Sheng was Vice-President of Neuroscience at Genentech, a leading biotech company, where he led research and drug discovery efforts for major diseases of the nervous system. This position in the Stanley Center for Psychiatric Research involves bioinformatics analysis in areas such as transcriptomics, neurophysiology, and behavior. Chan School of Public Health to study the genetics of severe mental illness, has recruited more than 42,000 participants in Ethiopia, Kenya, Uganda, and South Africa. Jin Sheng's Employment details. Please contact Prof. Sheng-Yang He (shengyang.he@duke.edu; hes@msu.edu). The Broad Institute of MIT and Harvard is looking for an exceptional candidate to join the Sheng lab or the Therapeutics group (led by Professor Morgan Sheng) in the Stanley Center for Psychiatric Research. Sheng completed his medical training and a residency in general medicine in London, UK. The Drug Repurposing Hub is one of the most comprehensive and up-to-date biologically annotated collections of FDA-approved compounds in the world. The NeuroGAP-Psychosis project, a collaboration between the Stanley Center for Psychiatric Research and Harvard T.H. Broad brings people together to advance the understanding and treatment of disease. infiniti qx80 indicator lights. In Situ Biology . Morgans unique perspective as a physician and scientist, along with his powerful commitment to translational neuroscience, will catalyze the Stanley Centers capacities for turning biological insights into new treatments for psychiatric illness, said Hyman. msheng@mit.edu. Research Scientist I - Therapeutics Group - Sheng Lab. A past recipient of the Fondation Ipsen Prize in Neuronal Plasticity and the Young Investigator Award of the Society for Neuroscience. Morgan Sheng is a core institute member of the Broad Institute of MIT and Harvard, where he serves as co-director of the Broads Stanley Center for Psychiatric Research. Zizhang Sheng is an associated research scientist in the Honig-Shapiro labs. I am looking forward to joining this community of innovative researchers and applying my expertise to discover novel therapies and improve the lives of people with mental illness.. Borislav Dejanovic, PhD (Staff Scientist/ Group Leader, Broad Institute), Sarah Wade (Research Associate, Broad Institute), Core Institute Member, Broad Institute of MIT and Harvard, Co-Director of the Stanley Center for Psychiatric Research at the Broad Institute, Office: Broad Institute, 75 Ames St. Room 9023. The inflammatory targets include cyclooxygenase-1 (COX-1), COX-2, and translocator protein (TSPO) and are studied in comparison to beta-amyloid and tau protein. 617-714-7022. Mobile Homes For Sale In Snyder County, Pa. Phone. Morgan Sheng, a neurobiologist and physician-scientist with deep experience in both basic research and drug discovery, has joined the Broad Institute of MIT and Harvard as its newest Core Member and as Co-Director of the institute's Stanley Center for Psychiatric Research. Excited & proud to share the work of #PeijunMa, a longtime friend & collaborator who led (in #DebHung 's lab . His research at Genentech focused on human genetics and pathogenic mechanisms of neurodegenerative disease, particularly Alzheimers and Parkinsons diseases. Job Description. (1st class honors) from Oxford University and obtained his medical degree and training at London University. Zhe Ji, Ph.D. Assistant Professor Postdoc in Systems Biology, Harvard Medical School Postdoc in Computational Biology, Broad Institute of MIT and Harvard Ph.D. in RNA Genomics, Rutgers University E Core Institute Members have their primary laboratories in the Broad Institute facilities. In a new study published in Oncogenesis, Zhi Sheng and Rob Gourdie of the Fralin Biomedical Research Institute at VTC describe how two protein-targeting drugs - when combined with chemotherapy - yield synergistic cytotoxicity to treatment-resistant glioblastoma. Dr. Sheng received his Ph.D. in Biochemistry from the University of Pennsylvania in 1993. is working in Medical laboratories activities. Pasadena, CA 91125. Massachusetts Institute of Technology. Requests for exemption for medical or sincerely held religious beliefs will be considered. The role will often involve rapid prototyping in support of a dynamic, fast-moving experimental program; it is focused on molecular biology applications relevant to investigation of brain function and psychiatric illness. 46-1303 Cambridge, MA 02139 . The Stanley Center aims to reduce the burden of serious mental illness by contributing new insights into pathogenesis, identifying biomarkers, and paving the way toward new treatments. He joined NINDS as an investigator in 1997 and is now a tenured senior investigator and Chief of Synaptic Functions Section at National Institute of Neurological Disorders and Stroke (NINDS), NIH. By creating this job alert, you agree to the LinkedIn User Agreement and Privacy Policy. Get notified about new Research Scientist jobs in United States. Ben joined the Engreitz Lab at the Broad Institute to develop experimental and computational tools to study enhancers and noncoding GWAS variants at single-cell resolution. Nonhematopoietic cells, including epithelial cells and stromal cells, are also important for enhancing or dampening inflammatory immune responses, especially at "barrier sites" such as the gastrointestinal (GI) tract and skin. By the end of 2022, Broads COVID-19 testing lab had processed more than 37 million tests. . Get email updates for new Research Scientist jobs in United States. Moreover, co-evolution between plants and microbes is greatly impacted by ongoing climate change. We join with institutions and scientists the world over to address foundational challenges in science and health. Research Focus: 3D genome architecture. We are seeking a motivated Computational Associate II (CA) to join the Sheng Lab at the Broad Institute of MIT and Harvard. Cambridge, MA 02139-4307 |(617) 253-5748, For Emergencies|Accessibility|Adapting to COVID, A physician and a scientist, Morgan Sheng. In back-fill mining, how to rapidly increase the concentration of tailings is an important problem facing mining engineers. Geplaatst op 3 juli 2022 door She leads the ICE-T (ion channel electrophysiology and technology) effort enabled by Broadnext10 initiative to utilize state-of-art technologies for studying ion channels and electrogenic transporters, and to find novel ways to modulate these highly specialized membrane proteins. Journal of Biological Chemistry 277 (8), 5699-5702, 2002. Published in NANO Letters, the study was led by Zhi Sheng and Deborah . Sheng received a B.A. In November 2022, Broads Genomics Platform sequenced its 500,000th whole human genome, a mere four years after sequencing its 100,000th. Raozhou Lin is a molecular neuroscientist with a keen interest in understanding the causes for neuropsychiatric diseases. 688 Timothy Johnson and lab technician David Rhodes for assistance in gnotobiotic system . Broad-spectrum disease resistance conferred by expression of the Pseudomonas syringae hrmA gene in plants (2001) Qingshun Li, Songhai Shen, Arthur Hunt and Sheng Yang He. Copyright 2008-2023, Glassdoor, Inc. "Glassdoor" and logo are registered trademarks of Glassdoor, Inc, The Broad Institute of MIT & Harvard is looking for outstanding postdoctoral scholars to join the laboratory of Morgan Sheng, Co-Director of the. Postdoctoral Associate - Sheng Lab. Yang uses biochemical and Lei is a postdoctoral researcher in the Pan Group at the Stanley Center for Psychiatric Research. Broad Institute 4.0. Chang MC, Srinivasan K, Friedman BA, Suto E, Modrusan Z, Lee WP, Kaminker JS, Hansen DV, Sheng M. J Exp Med. Hansen DV, Hanson JE, Sheng M. J Cell Biol. SPANGLER LAB. In 2021, our sustainability efforts sent more than 80 percent of waste from the Genomics Platform to either a recycling facility or to an incineration plant that generates electricity. Find out how to join the Broad as an employee or associate member. Is this useful? Pursuing these investigations will advance our knowledge of fundamental processes that may affect human neurological disorders. His work has uncovered the form and complexity of protein complexes in the postsynaptic membrane that regulate the remarkable plasticity of neuronal connections. The Stanley Center has gained unprecedented insight into the genetic basis of psychiatric illness (schizophrenia, bipolar disorder, autism). The broad conservation of plant microbiota suggests that plants . Receive regular updates on Broad news, research and community. By taking the advantage of next-generation sequencing technique, he uses bioinformatics approaches to investigate features of B cell repertoires, and to study mechanisms modulating the maturation process of broadly HIV-1 neutralizing antibody lineages in humans and animal models, with the aim of finding an optimal HIV . sweet things to write in a baby book. Sign in to create your job alert for Research Scientist jobs in United States. The Chen Lab. Research. From 2001 to 2008, Sheng was the Menicon Professor of Neuroscience at MIT, as well as an investigator of the Howard Hughes Medical Institute. At Genentech he built and led a world-class neuroscience department and research program focused on elucidating pathologic mechanisms and developing new treatments for neurodegenerative diseases and pain, and illuminating pathways that are of basic scientific interest as well as therapeutic relevance. Sheng started his academic career, centered on molecular and cellular neuroscience, in 1994 at Massachusetts General Hospital and Harvard Medical School, and later moved to MIT as the Menicon Professor of Neuroscience. M Sheng, S Smiga, A Bulfone, . All Companies Boston University (6) Brigham & Women's Hospital(BWH) (3) Northeastern University (2) Veeva (2) University of Massachusetts Medical School (2) Veeva Systems (2) Dana-Farber Cancer Institute (2) Berklee College of Music, Incorporated (1) The Broad Institute, Inc. (1) Mitsubishi Electric Research Laboratories (1) Suffolk University (1) Broad Institute (1) Boston Conservatory at . Biological products exc.diagnostic Umbilical cord blood stem cells and collection, storage, should be the technical services and research and development) Access free classroom materials and more for STEM educators, parents, students, tutors, and others. in chemistry with honors from Caltech in 1999, and a Ph.D. in chemistry from The Scripps Research . As Co-Director of the Stanley Center, Sheng will work with Stanley Center Director Steven Hyman to shape the centers scientific vision and direction, in addition to overseeing the centers therapeutic efforts, in conjunction with the Broads Center for the Development of Therapeutics. Requests for exemption for medical or sincerely held religious beliefs will be considered. The Merkin Institute is supporting early-stage ideas aimed at advancing powerful technological approaches for improving how we understand and treat disease. The Broad Institute of MIT and Harvard is looking for an exceptional candidate to join the Sheng lab or the Therapeutics group (led by Professor Morgan Sheng) in the Stanley Center for Psychiatric Research . Through programs spanning genetics, biology, and therapeutic development, Broad researchers are making discoveries that drive biomedical science forward. For a full list visit the lab website linked above. The Broad Institute of MIT & Harvard is looking for outstanding postdoctoral scholars to join the laboratory of Morgan Sheng, Co-Director of theStanley Center for Psychiatric Research, The mission of the Stanley Center is to improve the lives of patients suffering from serious mental illnesses, through groundbreaking basic and translational research.