Avoid everything that could cause a problem and result in another false positive for amphetamines. drbrush, Board Certified Physician. Brahm NC, Yeager LL, Fox MD, Farmer KC, Palmer TA. Vicks VapoInhaler [package insert]. False-positive results for methadone, opioids, phencyclidine, barbiturates, cannabinoids, and benzodiazepines were also reported in patients taking commonly used medications. The pain medication, . A recent study by Esposito et al published in the Journal of Analytical Toxicology showed that d-methamphetamine percentages often were a few percentage points above or below the expected value based on the standard solutions they were testing. This was due to impurities in some of the derivatizing agents used. Labetalol can also cause a false positive for amphetamine or methamphetamine because a labetalol metabolite is structurally similar to amphetamine. For this reason, immunoassay testing should be considered preliminary and presumptive. Answer. Yousuf SM, Alater AM, Alabdulla M, Osman M. Case Rep Psychiatry. Adderal Also causes a false positive methamphetamine test. When a reaction occurs, it is classified as 'positive' result. Clinical Interpretation of Urine Drug Tests: What Clinicians Need to Know About Urine Drug Screens. If youre taking labetalol, you could have a false positive test for amphetamine, methamphetamine, or LSD. is a drug commonly used to reduce the blood sugar of diabetic patients. Some point-of-care testing (POCT) devices may result in a false positive for amphetamines in patients who are taking certain prescription, over-the-counter, or illicit medications. Benzodiazepines also are regulary missed on enzyme immunoassay screens. In the United States, methamphetamine is a schedule II drug and is approved for treating both attention deficit hyperactivity disorder and obesity under the brand name Desoxyn. Thats because common over-the-counter medications can result in false positives for these substances. A retrospective chart review of 10,011 urine drug screens found that of 362 initial positive amphetamine tests, 128 (35%) were false positives. FOIA Prednisone is a corticosteroid that is detectable in your urine, so if you are taking the drug, it is possible that you will test positive for steroids. Dr. Brian Staiger is a licensed pharmacist in New York State and the founder of the Q+A website PharmacistAnswers.com. Available for Android and iOS devices. Unable to load your collection due to an error, Unable to load your delegates due to an error. 2023 SingleCare Administrators. They can distinguish between the l- and d-isomers of methamphetamine (only the d-isomer is psychoactive and illegal). Several medications can produce a false-positive result for methadone on the urine drug screen: diphenhydramine, doxylamine, clomipramine, chlorpromazine, quetiapine, thioridazine, and verapamil. PMC https://www.cdc.gov/nchs/fastats/drug-use-illicit.htm, https://www.samhsa.gov/workplace/resources, https://www.samhsa.gov/sites/default/files/workplace/2010GuidelinesAnalytesCutoffs.pdf, https://www.federalregister.gov/documents/2017/01/23/2017-00979/mandatory-guidelines-for-federal-workplace-drug-testing-programs, https://accesspharmacy.mhmedical.com/content.aspx?sectionid=210267566&bookid=2569#216818178, Amantadine, aripiprazole, atomoxetine, brompheniramine, bupropion, chlorpromazine, desipramine, DMAA, ephedrine, fluoxetine, labetalol, metformin, ofloxacin, phentermine, phenylephrine, phenylpropanolamine, promethazine, pseudoephedrine, ranitidine, selegiline, thioridazine, trazodone, nonprescription nasal antihistamine/decongestant inhalation, Baby wash products, dronabinol, efavirenz, ibuprofen, lamotrigine (on screenings for synthetic cannabinoids), naproxen, niflumic acid, proton pump inhibitors, Ambroxol, amitriptyline, benzphetamine, bupropion, buspirone, cephradine, chlorpromazine, desipramine, diltiazem, doxepin, fentanyl, fluoxetine, haloperidol, imipramine, labetalol, metoclopramide, prochlorperazine, risperidone, sertraline, thioridazine, trazadone, verapamil, ergonovine, lysergol, brompheniramine, imipramine, methylphenidate, fentanyl, sertraline, Diphenhydramine, doxylamine, chlorpromazine, clomipramine, doxylamine, quetiapine, thioridazine, verapamil, Amisulpride and sulpride, codeine, dextromethorphan, diphenhydramine, dihydrocodeine, morphine, methadone, morphine-3-glucuronide, creatinine, dihydrocodeine, levofloxacine, ofloxacine, morphine, naloxone, ofloxacin, petanzocine, psychotropic drugs, quetiapine, rifampicin, tapentadol, tramadol, verapamil, quinolones, quinine, Dextromethorphan, diphenhydramine, doxylamine, ibuprofen, imipramine, ketamine, lamotrigine, MDPV, meperidine, thioridazine, tramadol, venlafaxine. False positives on drug tests are unfortunately fairly common. October 12, 2022 by World Wide FAQS. Hair strand drug tests detect the presence of drug metabolites in the follicle. No cross-reactivity was found for other . Rifampin, an antibiotic used to treat tuberculosis, can also lead to a false positive result for opiates. As noted, the first test is the IA screening test. What exactly is Captagon and why was it banned? The d form is a prescription stimulant and appetite suppressant. He graduated from the University At Buffalo with a Doctor of Pharmacy degree in 2010. In one, , 49 out of 50 patients taking the drug tested positive for benzodiazepines. The commonly prescribed antidepressant, trazodone, has been reported to cause false positives in 3,4-methylenedioxymethamphetamine (MDMA) UDSs. A number of routinely prescribed medications have been associated with triggering false-positive UDS results, and the most commonly used tests to screen urine for drugs of abuse are immunoassays, even though false- positive results for drugsof abuse have been reported with a number of these rapid-screening products. Wygesic. "Our studies show that [the main targets in a hair test] can be present in hair of non . Researchers are studying how the body handles chemicals that may test . The FDA states that "certain foods, food supplements, beverages, or medicines can affect the results" of some drug tests. It is a common misconception that alcohol can cause a negative pregnancy test. you should drink of water per day. What Can Cause A False Positive For Methamphetamemes . These prescriptionsand other substancescan skew the results of a screen for illicit substances, Find out if caffeine interacts with these prescriptions for hypertension and heart problems. Can Certain Foods, Drinks, And Meds Cause A . Although this is not a high percentage, the consequences for failing a drug test could jeopardize your career, education, or job prospects. Epub 2015 Nov 2. Drug detection times An otherwise healthy 27-year-old female with a history of attention deficit hyperactivity disorder (ADHD) treated with atomoxetine had an acute onset tonic-clonic seizure. Amitriptyline. RELATED: Benadryl details | Doxylamine details. Additionally, a thorough medication history should be obtained to anticipate false-positive results. Its important to note that no drug test is 100% accurate. The Adderall will show up as a false positive for Methamphetamines. Welcome to JA Thanks for the question, Well a variety of substances can cause false positive testing for Methapmhetamines, most of them include;-Ephedrine, pseudo ephedrine, propylephedrine, phenylephrine Phenegan-D, Robitussin Cold and Flu Asthma medications Kidney infection, kidney disease, Liver disease, diabetes Many other prescription medications like Dexedrine, amifepramone, clobenzorex . J Anal Toxicol. " - Michael Lohan !!!. https://www.practicalpainmanagement.com/resources/diagnostic-tests/ask-expert-false-positive-amphetamine-urine-screens, Fenderson, J. L., Stratton, A. N., Domingo, J. S., Matthews, G. O., & Tan, C. D. (2013). The implications of potential false-positive urine drug screen (UDS) results for patients receiving commonly prescribed medications were evaluated. Deerfield, IL: Ovation Pharmaceuticals, Inc.; 2005. Drug tests are also performed in the workplace to identify illicit substance abuse. This acid-reducing medication is less effective when combined with certain food and drinksbut that doesnt mean you have to cut out caffeine entirely. Mandatory guidelines for federal workplace drug testing programs. Laboratory principles. Hair: Trazodone metabolites may be stored in the hair shafts and show up for a maximum of 90 days, similar to other illegal drugs. In very rare cases, you can have a false-positive result. Know if the meds you are taking might cause a false positive and notify the administrator of the test. Ranitidine. A drug metabolite is a remnant of the drug after being broken down by the body, and the most common metabolizer of a medication is the liver. Ofloxacin has also been shown to cause a false positive test for amphetamine or methamphetamine. The aim of this paper is to report the first case of atomoxetine leading to false-positive urine drug screen. Tim Thoelecke, CSAPA, is the founder of InOut Labs. government site. This might look like someone used illegal drugs (such as methamphetamines or opiates) when they did not. Metformin. In the 1970s, the drug was added to theschedule II listof controlled substances. While any discovery of metabolites in hair tests is believed to be undeniable proof of marijuana use, a new study from the Institute of Forensic Medicine in Freiburg, Germany finds that it's possible to get a false positive. Urine: Trazodone can show up in the urine for 5 to 26 days from the last use. A false positive is when a drug test shows the presence of a medication or substance that you didn't actually take. So, if you are like most people who dont take the time to study the fine print, here is a list of prescriptions and over-the-counter medications that could cause a false positive drug test. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Learn how we can help. The potential for psychotropic medications to cause false-positive results for methadone was also evaluated. Although this is not a high percentage, the consequences for failing a drug test could jeopardize your career, education, or job prospects. To quote a study published in the Journal of Clinical Biochemistry, " commonly used soap and wash products used for newborn and infant care as potential causes of false positive THC screening results .". Before False-positive results Amphetamine positive urine toxicology screen secondary to atomoxetine. Mebeverine (Duspatalin Retard 200 mg), an antispasmodic drug, has been described to cause false-positive amphetamine tests. and transmitted securely. Methamphetamine is illegal except when it is prescribed by a physician for a very limited number of medical conditions. Epub 2017 Mar 18. Hopefully I've answered your questions satisfactorily. Pract Pain Manag. Pseudoephedrine: Used for sinus and nasal congestion, pseudoephedrine (Sudafed) can be the cause of false positive tests for amphetamine or methamphetamine. According to the Drug Abuse Warning Network, 6.6% of emergency department visits involving illicit drugs in 2009 were due to methamphetamine.. , its highly unlikely that secondhand smoke will cause a false positive test for marijuana. All Rights Reserved. Levofloxacin (Levaquin) and ofloxacin are the most likely of the quinolone antibiotics to cause a false positive urine test for opiates. HHS Vulnerability Disclosure, Help I've also heard that Claritin (the allergy medication) can,. Roopa Sethi, MD; Amad Din, MD, MPH; Ryan McAllister, MD; and Andrew Lester, MD. If you're taking labetalol, you could have a false positive test for amphetamine . This might look like someone used illegal drugs (such as methamphetamines or opiates) when they did not. The d,l-isomer test also is performed by MS. Understanding each of the 3 testing steps is essential to clinical decision making related to patient care. Baby Soap. It didn t how much can lifestyle changes lower blood pressure say who the roasted whole sheep belonged to, So Al grabbed this guy, and the final result was very unexpected. What Medications Can Cause A False Positive For Methamphetamemes Online Shop Are Blood Pressure Meds Fast Acting Rubbing Neck To Lower Blood Pressure Horse Chestnut And Blood Pressure Meds What Helps High Blood Pressure Go Down What Medications Can Cause A False Positive For Methamphetamemes.. And counting the time, it has been blood pressure meds and chronic cough nearly a day since what . Multiple medications can cause false positive results. Mayo Clin Proc. If it is an OTC product, have some kind of documentation (the container it was in, a note from your physician, etc.) For example, an immunoassay for cannabinoids that resulted in a false-positive from ibuprofen was corrected over 20 years ago. Hemodynamic Effects of Methamphetamine and General Anesthesia. International Agency for Research on Cancer - Screening Group. A Retrospective Analysis of Urine Drugs of Abuse Immunoassay True Positive Rates at a National Reference Laboratory. Additionally, GC-MS quantifies the amount of drug present in a sample. Additionally, it is important to note which opioids are included on an institutions standard screening, as certain opioids may require an additional order or GC-MS. Summary Quinolone antibiotics: Quinolone antibiotics such as levofloxacin (Levid 500), ofloxacin and ciprofloxacin are commonly prescribed for urinary tract infections, pneumonia, and sinus infections among other things. All of the following medications have documented cases of causing a false positive for either amphetamine or methamphetamine: Amantadine. Although the affinity of the antibody for these substances is much lower than for fentanyl, if they are present at sufficiently high concentrations, they can cause a false positive result [24, 25]. If I took 1/4 of a 5mg tablet in the morning and had a urine drug test that afternoon will it show positive even if only a trace? Often times, drugs that are NOT being tested for can react with the wrong antibody (i.e. Careers. Urine drug testing screens for the presence of THC, the psychoactive component of marijuana, but a problem could arise due to the fact that these products are not very well-regulated and cross contamination can occur. Cold remedies, hay fever remedies, nasal decongestants, diet pills, fluoxetine (Prozac), methylphenidate (Ritalin), bupropion (Wellbutrin), beta blockers (blood-pressure remedies) Barbiturates. Methamphetamine Information for Consumers, Methamphetamine Information for Healthcare Professionals, DMAA (1,3-dimethylamylamine), found in some dietary and weight-loss supplements, DeGeorge, Jr. M, Weber J. Methamphetamine Urine Toxicology: An In-depth Review. Sohal S, Sous M, Pethe G, Padmanabhan SV, Akbari R, Dadkhah S. Case Rep Med. When it comes to prescriptions, warnings are available, but usually only if you look for them, says Brent McFadden, Pharm.D., the owner of Brents Pharmacy & Diabetes Care in St. George, Utah. I would appreciate it if you please leave a five star rating at the top left part of your screen, since this is the only way I have tank credit for this answer. University of Illinois at Chicago College of Pharmacy. Categories of medications included antihistamines, antidepressants, antibiotics, analgesics, antipsychotics, and nonprescription agents. October 18, 2018. Safdari KM, Converse C, Dong F, MacDougall NA, Hyer K, Runyon A, Ahlering H, Comunale ME. Ofloxacin may also cause a false positive result for amphetamine or methamphetamine. 2021 Oct 27;13(10):e19082. However, these antibodies may detect drug metabolites with similar structure and characteristics to methamphetamine, leading to false-positive results. I Have Never Used Methamphetamine, But My Urinalysis Says I Do. https://doi.org/10.1016/s0196-0644(05)80433-0, Caricasole, V., Spagnolo, G., Di Bernardo, I., Cirnigliaro, G., Piccoli, E., & DellOsso, B. 2017 May;92(5):774-796. doi: 10.1016/j.mayocp.2016.12.007. Amphetamines and methamphetamines are part of an important class of drugs included in most urine drugs of abuse screening panels, and a common assay to detect these drugs is the Amphetamines II immunoassay (Roche Diagnostics). Bethesda, MD 20894, Web Policies Bupropion (generic Wellbutrin). 2021 Nov 30;2021:7134394. doi: 10.1155/2021/7134394. The MS confirmation test can come back with 4 possible results: 1) no amphetamines detected; 2) amphetamine only detected; 3) methamphetamine only detected; and 4) both amphetamine and methamphetamine detected (Figure 1). Opiate immunoassays detect morphine and codeine, the major metabolites of heroin and a common contaminant acetylcodeine, respectively.11 Therefore, they do not reliably detect semisynthetic and synthetic opioids. A comparison of the chemical structures of . https://dig.pharmacy.uic.edu/faqs/2021-2/may-2021-faqs/what-drugs-are-likely-to-interfere-with-urine-drug-screens/. Some examples include NSAIDs, dextromethorphan, and some antidepressants. Abuse and misuse of prescription and illicit drugs is a growing concern, with 11.7% of the U.S. population over 12 years of age reporting illicit drug use in 2018, an increase from 7.9% in 2004.1,2 Drug testing is frequently used in clinical setings to identify substance-use disorders, confirm medication adherence, or identify overdoses. , may produce a false positive drug test. Can Albuterol Cause a False Positive Drug Test? Amphetamine. Please enable it to take advantage of the complete set of features! The first test is an immunoassay (IA) screening test for the amphetamine class of medications, which includes both amphetamines and methamphetamines. If you have been on all these meds before and you have been tested clean then the only answer is the 95% rule. Didrex [package insert]. In addition, benzphetamine (Didrex) is a schedule III medication approved for treatment of obesity. 2016 Mar;40(2):97-107. doi: 10.1093/jat/bkv133. Based on how urine drug tests work, it makes sense that anticonvulsant drugs have a . On arrival to the hospital, a urine toxicological drug screen with immunochemical cloned enzyme donor immunoassay . It is usually in the fine print and most people, in my experience, dont read the material given to them by the pharmacist.. In addition to false-positive results, there are several notable limitations of immunoassay urine screens that can lead to false-negative results.6 Enzyme immunoassays used for amphetamines have low sensitivity to certain drugs commonly used in the rave scene, such as 3,4-methylenedioxyamphetamine (MDA) and 3,4-methylenedioxyamphetamine (MDMA), and they are unable to detect phenethylamine-based bath salts. My question Im in pain mgmt and I take norco as needed everyday. Eldepryl [package insert]. Results from the 2011 National Survey on Drug Use and Health: Summary of National Findings. eCollection 2021 Oct. False-positive interferences of common urine drug screen immunoassays: a review. Pseudoephedrine, the decongestant found in original Sudafed (the kind you have to sign for) can/will cause a false positive under one of those two test columns. Urine is most commonly used due to its ease of collection. US Pharm. We recommend using the latest version of IE11, Edge, Chrome, Firefox or Safari. And certain drugs, such as tranquilizers, anticonvulsants, or hypnotics, may also cause false-positive results. Prescription use of propoxyphene may cause a positive test result because the cut-off concentration for propoxyphene in urine (300 ng/mL) can be reached after medical use of this drug. 833 S. Wood St., Suite B12, College of Pharmacy, (MC 886), Chicago, IL 60612, 2023 The Board of Trustees of the University of Illinois, UI Health is UICs academic health enterprise. People taking the HIV medication Sustiva (efavirenz) may obtain false positive drug test results. For example, Wellbutrin (bupropion), Prozac (fluoxetine), and Desyrel (trazodone) can all potentially show up as amphetamines in a drug screen. Let outsiders enter, so our understanding of the strength of what medications can cause a false positive for methamphetamemes their students is very superficial. There are a few distinct sources of methamphetamine. False positive results for methamphetamine occur about 10 to 15 times out of 100 tests and it is usually due to one major reason, Insufficient Laboratory Tests for Confirmation, although other reasons can be added. New DOT Drug Testing Cutoff Levels 2021/2022. UIC's seven health sciences colleges and health care delivery enterprise. Introduction 12. Ibuprofen is still frequently reported in resources as a possible cause for false-positive cannabinoid immunoassays. The weight loss drug phentermine, may produce a false positive drug test. J Anal Toxicol. Besides prescription sources, methamphetamine (ie, crystal meth) can also be produced in small, clandestine laboratories using ephedrine or pseudoephedrine as a key ingredient. warnings are available, but usually only if you look for them, s. It is usually in the fine print and most people, in my experience, dont read the material given to them by the pharmacist. The challenge most times for the laboratory is to differentiate between the d and the l isomer forms of methamphetamine. If, under their physicians approval, the person can be off the medicine for that length of time, a negative test should result.. During World War 2, methamphetamine similar in structure to amphetamine was usedto keep military personnel alert and to improve endurance and mood. According to research, its highly unlikely that secondhand smoke will cause a false positive test for marijuana. Results are relatively rapid, and the test can screen for a wide variety of drug metabolites. , and are well known to cause a false positive for amphetamines and methamphetamines. 5-7 Non-amphetamine prescription, illicit, or over-the-counter . Quetiapine, which treats schizophrenia and bipolar disorder, can wrongly show that you have methadone in . Substance Abuse and Mental Health Services Administration, Drug Abuse Warning Network, 2009: National Estimates of Drug-Related Emergency Department Visits. Psychiatrist.com https://www.psychiatrist.com/pcc/addiction/substance-use-disorders/i-have-never-used-methamphetamine-but-my-urinalysis-says-i-do/#:~:text=1%2D4%20Common%20medications%20that,bupropion%2C%20trazodone%2C%20and%20chlorpromazine. Standridge JB, Adams SM, Zotos. Hair drug test: Positive doesn't always mean positive. 8600 Rockville Pike What drugs are likely to interfere with urine drug screens? Accessed October 4, 2012. Purpose. Discovered in the late 19th century, amphetamine was first used as a nasal decongestant and a respiratory stimulator. Generally, there are two methods for drug testing using urine samples; they are the definitive and presumptive drug monitoring tests. Each drug varies in the amount of time it can be detected in the urine (Table 2).2 The detection time is primarily based on half-life and the presence of drug metabolites. Federal government websites often end in .gov or .mil. READ What Does M AMP Stand For On A Drug Test? Drug testing can be performed using various biologic specimens, including urine, saliva, hair, sweat, nails, meconium, and blood. HHS Publication No. quinine, and when consumed in large amounts could lead to, Coca tea is made from coca leaves, which are part of the coca plant from which. Key points. Infants tend to have more dilute urine, which reaches adult osmolarity around the age of 2 years. Similarly, gabapentin is very unlikely to cause a false positive for other drugs. 13. Esposito FM, Crumpton S, Mitchell J, Flegel RR. Many medicines you can purchase at your local chemist containing pseudo-ephedrine, ephedrine, or other sympathomimetic amines tend to interfere with urine screening tests and cause false positive results for amphetamines, but do not cause positive test results in the gas chromatography/mass spectrometric, or GC/MS, confirmation, thus pose no . Pract Pain Manag. Medical exposure to cocaine RELATED: Learn the dangers of a cough syrup addiction. A finding of amphetamine-only positive by MS can be caused by prescription drugs (Adderall and various amphetamine salts) or as a result of methamphetamine metabolism, where the methamphetamine (whatever the source) has been converted to amphetamine. It is also a good idea to avoid taking any vitamins or similar supplements until you take the test. Alcohol does not affect the accuracy of pregnancy tests. Five common medications can cause a false positive for methamphetamine. Pract Pain Manag. Toxicology. It can show up as positive for meth on a drug test though. There is no definitive research suggesting that other drugs can cause a false positive for gabapentin, aside from Lyrica (pregabalin), a drug closely related to it. Annals of emergency medicine, 22(12), 19271928. Sertraline (Zoloft) Sertraline is used to treat depression, panic attacks, obsessive compulsive disorder, post-traumatic stress disorder, social anxiety disorder (social phobia), and a severe form of . Furthermore, if they can prove they are taking a medicine that can produce a false positive (by producing a legitimate prescription), the administrator may schedule another test 30 to 60 days later. Epub 2014 Jul 1. Conclusion: Using current methodology for urine toxicology testing will allow clinicians to narrow down the possible source of a positive result and assist them in managing their patients accordingly. InOut Labs is a nationwide provider of employee drug testing services, and your best choice for affordable, direct-to-consumer health tests. This test is more specific than immunoassay testing, as it detects drugs by molecular structure. The clinician needs this critical information because without the d:l-isomer ratio, the clinician is unable to narrow down the potential sources of the methamphetamine. With CBD available in everything from drink powders, to weight loss formulations, to tinctures of all types, false positive urine screenings for THC will become more and more common, warns Dr. McFadden. Purpose: Cincinnati, OH: Procter & Gamble; 2010. Accessed October 9, 2012. Immunoassay testing for methamphetamine uses antibodies to look for certain drug metabolites (these are the compounds a drug breaks down into), and is the most common test used for initial screening. Comprehensive Psychiatry, 94, 152126. https://doi.org/10.1016/j.comppsych.2019.152126. Drug concentration level thresholds are used in reporting of positive and negative reports for urine drug testing.2 If a test detects a concentration above the threshold, it is reported as positive, and vice versa for negative results. ABSTRACT: Urine drug screening is a common way to test for compliance with medications having high abuse potential. Please enable JavaScript!Bitte aktiviere JavaScript!S'il vous plat activer JavaScript!Por favor,activa el JavaScript!antiblock.org. Urine drug testing is frequently performed by immunoassay (IA) due to ease of use, rapid turn-around time and the ability to screen multiple drug classes. When consumed in large quantities (such as in a poppy seed bagel or muffin), the tiny black seeds might cause a false positive drug result for opioids. Can OTC and prescription drugs affect a pregnancy test? What causes a false positive? It is intended for general informational purposes and is not meant to be a substitute for professional medical advice, diagnosis, or treatment. When methamphetamine is detected or both amphetamine and methamphetamine are detected, then the lab can run a d,l-isomer test to try and narrow the source of the positive methamphetamine finding (Figure 1). This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Public Health Nigeria Public Health Nigeria an Interdisciplinary public health movement focused on health education, advancing fair public health policies, promoting fitness, healthy diets, responsible behavior, community health and general wellbeing. on What Can Cause A False Positive For Methamphetamines? It increases the levelsof naturally occurring dopamine and norepinephrine in the brain. There are many different over the counter and prescription medications that have been reported to cause false positives for methamphetamine on a drug test. Immunoassay technology uses antibodies to detect drug metabolites. When interpreting test results, a clinician should consider that the result might never be 100% d or l isomer due to these impurities. official website and that any information you provide is encrypted Taking Sudafed can result in a false positive for amphetamine or methamphetamine. (pseudoephedrine) is also the main ingredient to the making of. [PMID 23088194] Follow me on Twitter . In addition to prescription medications, these other common substances can lead to a false positive drug test.